UKE Microscopy Imaging Facility (DFG Research Infrastructure Portal: RI_00489)


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MINFLUX microscopy made the visualization of SARS-CoV2 virus molecules possible. (1) Confocal, (2) MINFLUX, (3) MINFLUX superimposed with EM, (4) schematic overlay with SARS-CoV2 model

Confocal microscopy III

Mouse hippocampus

GFAP (for astrocytes) / Iba-1 (microglia) / Hoechst (nucleus). Author: Prof Saez

Confocal microscopy I

Optical nerve

tiled scan

Confocal microscopy II

Heart tissue section

Super-resolution image of detyrosinated tubulin.

Detyrosinated tubulin in neurons.

left = confocal, right = STED

Super-resolution 3D dSTORM image of microtubules

Alpha-tubulin in HeLa cells.

Color-coded z-distribution.

Structured illumination microscopy (SIM)

Multicolor labeling of an eukaryotic cell.

red =actin, green = focal adhesions, blue = DAPI

Combined SD-TIRF imaging of cellular vesicles

3D reconstruction of CLN3-vesicles and lysosomes in HeLa cells.

green = CLN3-GFP, red = lysosomes

Super-resolution radial fluorescence microscopy (SRRF)

Mutli-color HeLa cells

green = F-Actin red = alpha-Tubulin gray = TOMM-20

Olympus AI Image Analysis Lunch&Learn Webinar

This interesting webinar (07.12.2021 between 11:30-12:30) will focus your attention on  a novel approach to quantify your imaging data, teaching the computer how to do it: deep learning.
If you are curious and you would like to know how it works, what it can do and how it can impact your research please do not hesitate to join, it is for free and you are warmly invited!!!
When you send the registration email  (in order to get the webinar link) please make Dr. Antonio Virgilio Failla in cc (a.failla{at}
Please extend the invitation to anyone you think might be interested!

Olympus AI webinar

CREST X-Light workshop

In the frame of the UMIF workshop series 2021/2022, there will be an exciting webinar about the CREST X-Light V3 L-FOV Spinning Disk Confocal System.

It will take place on 26th November 2021 @ 10 a.m., and you can register via the form >>>>> HERE <<<<< to receive the webinar link.

The CREST X-LIGHT V3 L-FOV Spinning Disk confocal System is a customizable dual-camera system with a large field of view, integrated into Nikon's inverted microscope platform (Ti2 + NIS-Elements software). If you are interested, please register and share this information.

Are you also interested in testing the system with your own samples? Hands-on session will be possible between 02.12.-10.12.2021 at Campus Forschung. Please send an Email to a.failla{at} and Dr. Antonio Virgilio Failla will organize a testing slot for you.

CREST X Light workshop

Course "Light microscopy from single molecule to live embryo"

Dear all
in collaboration with the university of Tübingen I am giving a series of lectures about light microscopy.
The lectures are strongly biologically oriented but there will be presented also Nano-technological applications.
Please find more information about how to join the course and about the topics that will be presented in this >> FILE << and in the individual lectures in the Event section of this webpage.

If you are interested please register sending email to This email address is being protected from spambots. You need JavaScript enabled to view it. .

You are all warmly invited to join and to extend this invitation to anyone you think might be interested.
Best wishes
Antonio Virgilio Failla

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