UMIF

UKE Microscopy Imaging Facility (DFG Research Infrastructure Portal: RI_00489)

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MINFLUX

SARS-CoV2

MINFLUX microscopy made the visualization of SARS-CoV2 virus molecules possible. (1) Confocal, (2) MINFLUX, (3) MINFLUX superimposed with EM, (4) schematic overlay with SARS-CoV2 model

Confocal microscopy III

Mouse hippocampus

GFAP (for astrocytes) / Iba-1 (microglia) / Hoechst (nucleus). Author: Prof Saez

Confocal microscopy I

Optical nerve

tiled scan

Confocal microscopy II

Heart tissue section

Super-resolution image of detyrosinated tubulin.

Detyrosinated tubulin in neurons.

left = confocal, right = STED

Super-resolution 3D dSTORM image of microtubules

Alpha-tubulin in HeLa cells.

Color-coded z-distribution.

Structured illumination microscopy (SIM)

Multicolor labeling of an eukaryotic cell.

red =actin, green = focal adhesions, blue = DAPI

Combined SD-TIRF imaging of cellular vesicles

3D reconstruction of CLN3-vesicles and lysosomes in HeLa cells.

green = CLN3-GFP, red = lysosomes

Super-resolution radial fluorescence microscopy (SRRF)

Mutli-color HeLa cells

green = F-Actin red = alpha-Tubulin gray = TOMM-20

http://microscopy-hamburg.de

The Hamburg microscopy community starts to build up a network to share resources, ideas, news and microscopy related problems.

The virtual meeting point for this community will be http://microscopy-hamburg.de/.

Please visit it and, in case, your feedback will be welcome.

Open position at Abberior Instruments

If someone of you is potentially interested to work in the industry direction microscopy please consider the job offer of the company Abberior (leader in super resolution optical microscopy) below.

abberior position

JASN journal cover May 2019

The cover picture of the May 2019 issue of the Journal of the American Society of Nephrology highlights the work of J. Herwig et al. from the group of C. Meyer-Schwesinger (Institute of Cellular and Integrative Physiology, UKE). Congratulations to all the authors! In collaboration with A.V. Failla from our facility, a range of microscopes and techniques were successfully applied, such as STED super-resolution. Please find more information in our publication section. 

JASN cover May2019

Page 8 of 9

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